Free Clinical Tool

HOMA-IR Calculator

Instantly evaluate your insulin resistance and beta-cell function from fasting blood test lab results.

Fasting Blood Glucose
mg/dL
Fasting level (normal range: 70 – 99 mg/dL)
Fasting Insulin
µU/mL
Basal fasting insulin (normal range: 2.6 – 24.9 µU/mL)
Your HOMA-IR Score
0.00
Normal
<1.0 Optimal 1.0–1.9 Normal 2.0–2.4 Borderline ≥2.5 Resistance ≥3.5 Severe
Beta-Cell Function Estimate (HOMA-β):
Secretory capacity of pancreatic beta cells (normal: 100%)
N/D
How to Interpret HOMA-IR Results

How to Interpret HOMA-IR Results

The HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) index measures how effectively cells respond to insulin after an 8–12 hour overnight fast.

HOMA-IR Score Classification Clinical Significance
< 1.0 Optimal (High Sensitivity) Excellent insulin sensitivity (HOMA-IR Minimal cardiometabolic risk.
1.0 – 1.9 Normal Range Normal insulin sensitivity (1.0 – 1.9). Healthy carbohydrate metabolism with balanced glucose regulation.
2.0 – 2.4 Borderline / Early Resistance Borderline zone (2.0 – 2.4). Tissues require increased insulin. Ideal window for dietary and exercise intervention.
2.5 – 2.9 Insulin Resistance Confirmed insulin resistance (HOMA-IR ≥ 2.5). Pancreas compensates by overproducing insulin (hyperinsulinemia). Medical consultation recommended.
≥ 3.0 Severe Insulin Resistance Marked insulin resistance (HOMA-IR ≥ 3.5). Highly associated with metabolic syndrome and type 2 diabetes risk.

HOMA-IR Calculation Formula

HOMA-IR = (Glucose [mg/dL] × Insulin [µU/mL]) ÷ 405

SI Units (mmol/L):
HOMA-IR = (Glucose [mmol/L] × Insulin [µU/mL]) ÷ 22.5

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Frequently Asked Questions (FAQ)

What does a high HOMA-IR mean?
A score of 2.5 or higher indicates insulin resistance, meaning the pancreas must produce excess insulin to maintain normal blood sugar levels.
What blood tests are required for HOMA-IR?
You only need two fasting measurements from a single blood draw: fasting plasma glucose and fasting serum insulin.
Can insulin resistance be reversed?
Yes. In most cases, adopting a low-glycemic high-fiber diet, regular strength and aerobic exercise, and optimizing sleep can restore insulin sensitivity.

Keep Track of Your Daily Glucose

Tracking daily blood glucose before and after meals helps your physician optimize insulin therapy and diet. Check out our pocket-sized diabetes log book.

Overspire Pocket Blood Sugar Log Book See on Amazon.com (4.5★)
Medical Disclaimer: This calculator is intended strictly for educational and informational purposes and does not replace medical advice or diagnosis. Always consult a healthcare professional.